Tourism is a”smokeless industry”that contributes to increasing national income and creating jobs for a large part of the workforce. Today, many countries in the world, including Vietnam, have prioritized the development of tourism as a key industry in their country. And there are also some countries that choose Vietnam as a place to invest in the tourism industry. With the current situation, Vietnam is in the process of international integration with rich human resources that are suitable for making business decisions of foreign corporations with favorable factors but also other factors. Adverse factors such as the 4.0 technology race with the latest technologies in production and business, but skilled human resources to use are still limited. From the analysis of factors affecting the business decision-making process at foreign corporations operating in Vietnam recently, the article will analyze in depth the factors affecting the business decision-making process and solutions to overcome the influencing factors.